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Stand Alone Protein Characterisation

Cobra offers comprehensive packages for the physicochemical characterisation of mammalian and microbial protein products, and where appropriate more than one analytical procedure employing different analytical principles will be applied. 

The characterisation packages are adapted to the requirements of the product in order to comply with ICH guidelines especially for antibodies and biosimilars. Structural characterisation and conformation can be examined, as well as amino acid, peptide mapping and disulphide bridge analysis.
For carbohydrate structures we can carry out analysis of monosaccharide composition, sialic acid content and also perform oligosaccharide profiling and glycosylation site characterisation, whilst looking at post-translational modifications.

Physicochemical properties can be examined via molecular weight or size, alongside isoform pattern and electrophoretic profiling.

Please don't hesitate to get in touch if you would like to find out more.

Other Stand Alone Services...

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