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What is PEGylation?

PEGylation plays a key role in modern drug delivery, maximizing the potential of the therapeutic substance.
PEGylation is the modification of a protein, peptide or non-peptide molecule, by linking polyethylene glycol (PEG) chains, to extend a drugs effect by reducing degradation and reducing the rate of excretion by the kidneys and the formation of antibodies against the protein.

PEGylation (also often style pegylation) is the process of covalent attachment of polyethylene glycol (PEG) polymer chains to another molecule, normally a drug or therapeutic protein, which is then described as PEGylated (pegylated). (Wikipedia)

PEGylated (peg'i-lāt-ed), Substance with chemically attached glycol moieties. [PEG (polyethylene glycol) +- yl, chemical siffix, + -ated, pp. suffix] (Farlex Partner Medical Dictionary)


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